Biotechnology for the Non-Biotechnologist

Course Info

Length: 1 Week

City: Kuala Lumpur

Type: In Classroom

Available Dates

  • Mar-25-2024

    Kuala Lumpur

  • Apr-22-2024

    Kuala Lumpur

  • May-27-2024

    Kuala Lumpur

  • June-24-2024

    Kuala Lumpur

  • July-22-2024

    Kuala Lumpur

  • Aug-26-2024

    Kuala Lumpur

  • Sep-23-2024

    Kuala Lumpur

  • Oct-28-2024

    Kuala Lumpur

  • Nov-25-2024

    Kuala Lumpur

  • Dec-23-2024

    Kuala Lumpur

Dates in Other Venues

  • Mar-11-2024

    Barcelona

  • Mar-11-2024

    Dubai

  • Mar-18-2024

    Amsterdam

  • Mar-18-2024

    London

  • Mar-25-2024

    Istanbul

  • Apr-01-2024

    Paris

  • Apr-01-2024

    Singapore

  • Apr-08-2024

    Barcelona

  • Apr-08-2024

    Dubai

  • Apr-15-2024

    London

  • Apr-15-2024

    Amsterdam

  • Apr-22-2024

    Singapore

  • Apr-29-2024

    Istanbul

  • Apr-29-2024

    Paris

  • May-06-2024

    Paris

  • May-06-2024

    Singapore

  • May-13-2024

    Dubai

  • May-13-2024

    Barcelona

  • May-20-2024

    London

  • May-20-2024

    Amsterdam

  • May-27-2024

    Istanbul

  • June-03-2024

    Paris

  • June-03-2024

    Singapore

  • June-10-2024

    Barcelona

  • June-10-2024

    Dubai

  • June-17-2024

    London

  • June-17-2024

    Amsterdam

  • June-24-2024

    Istanbul

  • July-01-2024

    Paris

  • July-01-2024

    Singapore

  • July-08-2024

    Dubai

  • July-08-2024

    Barcelona

  • July-15-2024

    London

  • July-15-2024

    Amsterdam

  • July-22-2024

    Singapore

  • July-29-2024

    Istanbul

  • July-29-2024

    Paris

  • Aug-05-2024

    Paris

  • Aug-05-2024

    Singapore

  • Aug-12-2024

    Barcelona

  • Aug-12-2024

    Dubai

  • Aug-19-2024

    Amsterdam

  • Aug-19-2024

    London

  • Aug-26-2024

    Istanbul

  • Sep-02-2024

    Paris

  • Sep-02-2024

    Singapore

  • Sep-09-2024

    Dubai

  • Sep-09-2024

    Barcelona

  • Sep-16-2024

    London

  • Sep-16-2024

    Amsterdam

  • Sep-23-2024

    Singapore

  • Sep-30-2024

    Paris

  • Sep-30-2024

    Istanbul

  • Oct-07-2024

    Paris

  • Oct-07-2024

    Singapore

  • Oct-14-2024

    Barcelona

  • Oct-14-2024

    Dubai

  • Oct-21-2024

    London

  • Oct-21-2024

    Amsterdam

  • Oct-28-2024

    Paris

  • Oct-28-2024

    Singapore

  • Oct-28-2024

    Istanbul

  • Nov-04-2024

    Singapore

  • Nov-04-2024

    Paris

  • Nov-11-2024

    Dubai

  • Nov-11-2024

    Barcelona

  • Nov-18-2024

    Amsterdam

  • Nov-18-2024

    London

  • Nov-25-2024

    Istanbul

  • Dec-02-2024

    Paris

  • Dec-02-2024

    Singapore

  • Dec-09-2024

    Dubai

  • Dec-09-2024

    Barcelona

  • Dec-16-2024

    Amsterdam

  • Dec-16-2024

    London

  • Dec-23-2024

    Singapore

  • Dec-30-2024

    Istanbul

  • Dec-30-2024

    Paris

Course Details

Course Outline

5 days course

 

Introduction to Biotechnology
 
  • Historical perspective
  • Diversity of biotechnology products
  • Impact on society
  • Product development overview

 

Introduction to Molecular Biology

 

  • DNA, RNA, genes, plasmids and vectors
  • Protein synthesis – transcription and translation

 

Re-expression of proteins

 

  • Recombinant DNA techniques
  • Monoclonal antibodies – from mouse to human
  • Transgenic animals and plants

 

Development of Production Organisms

 

  • Transfection
  • Selection
  • Preservation

 

Fermentation Technology and Large-Scale Production

 

  • Types of fermenters
  • Fermentation basics
  • Modes of operation
  • Process development

 

Process Optimisation and Scale-up

 

  • Scale-up strategies
  • Strain improvement
  • Media improvement
  • Process improvement

 

Analysis of Biopharmaceuticals

 

  • Biological activity
  • Physicochemical characterisation
  • Purity, impurities and contaminants

 

Product Recovery and Purification

 

  • Cell harvesting and removal
  • Clarification – intracellular and extracellular proteins
  • Chromatographic techniques

 

Formulation Design of Biopharmaceuticals
 
  • Factors affecting degradation
  • Choice of excipients
  • Prolonging shelf life

 

Process Economics

 

  • Drug development and bioprocess economics
  • Optimising bioprocess economics
  • Manufacturing make or buy
  • Future manufacturing alternatives

 

Patenting Biotech Inventions

 

  • What is a patent?
  • What are the basic criteria for patentability?
  • What can be patented?
  • Can you patent genes, proteins, hybridomas, and stem cells?

 

Patent Workshop

 

  • How to recognise what is patentable
  • Drafting claims to biotech inventions
  • Maximising protection for an invention
  • Understanding the examination process
  • Enforcing patents

 

Regulatory Considerations of Biopharmaceuticals

 

  • General principles
  • Product quality and control
  • Pre-clinical safety

 

Application of Regulatory Principles

 

  • What do regulators want?
  • Specifications
  • Product characterisation
  • Assessment of process change
  • Comparability guidance and strategy

 

Advances in Regulation: Biosimilars

 

  • Comparability, equivalence and biosimilarity
  • Biosimilars guidance
  • Guidance vs practice – a case study

 

Advances in Regulation: Advanced Therapies

 

  • Gene therapy
  • Cell therapy
  • Tissue-engineered products

Course Video